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. Author manuscript; available in PMC: 2023 Jan 13.
Published in final edited form as: Nature. 2022 Jul 13;607(7919):610–616. doi: 10.1038/s41586-022-04939-z

Extended Data Figure 7: GATOR2 RING domains are incompatible with E2 binding.

Extended Data Figure 7:

Structural alignment between GATOR2 CTD-CTD junctions and the RNF4-UBCH5A complex (PDB ID: 4AP4)17. Individual CTD pairs are drawn (left) and superimposed with RNF4-UBCH5A (right) as follows: (a) WDR24-MIOS, (b) MIOS-WDR24, (c) MIOS-WDR59, and (d) WDR59-MIOS.