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. Author manuscript; available in PMC: 2022 Dec 13.
Published in final edited form as: Clin Cancer Res. 2022 Jun 13;28(12):2587–2597. doi: 10.1158/1078-0432.CCR-21-3215

Figure 2. Differentially expressed genes between pCR and RD in basal-like immune-rich TNBC.

Figure 2.

(A-G) Volcano plots of differentially expressed genes in immune high cancers defined by sTILs ≥ 30 %, PD-L1 positive, TIS > 0.1249, GS > 0.26, NHI 5-gene score > 0.0014, STAT1 score > 0.07695, or IFNG ≥ 0.20, respectively. Statistically significant genes are in red, top 50 significant genes annotated in blue. sTILs = stromal tumor infiltrating lymphocytes. TIS = Tumor inflammation signature. GS = GeparSixto signature. IFNG = interferon gamma single gene.