Figure 2.

Association between Baseline Medication Count and Potential Impact of Pediatric MTM Approach

Panel A illustrates the association between baseline medication count and the number of interventions identified through the standardized pediatric MTM approach. The number of identified interventions was significantly higher in patients with higher medication counts; mean intervention count was 3.5 (95% CI: 3.0–4.0), 6.5 (95% CI: 5.5–7.5), and 8.0 (95% CI: 6.7–9.3) in patients using 5–9 medications, 10–14 medication, and ≥15 medications at the time of the index visit, respectively (all p<0.001). Panel B illustrates the association between baseline medication count and the magnitude of the pediatric MTM’s potential effect on MRCI score. Impact of the proposed pediatric MTM intervention on MRCI score was also significantly greater in patients with higher counts; mean MRCI reduction was 2.9 points (95% CI: 2.0–3.7) in patients using 5–9 medications, 5.7 (95% CI: 3.6–7.8) in patients using 10–14 medications, and 10.7 (95% CI: 7.5–13.8 in patients using ≥15 medications at the time of the index visit (all p<0.001), Each data point represents an individual patient from the study cohort. Solid blue lines indicate the thresholds used for stratification and analysis.