APTT | Activated partial thromboplastin time |
Ara-C | Cytosine arabinoside |
AST | Aspartate aminotransferase |
BBB | Blood–brain barrier |
CAR-T | Chimeric antigen receptor T |
CNS | Cerebral nervous system |
CR | Complete remission |
Cr | Creatinine |
CRP | C-reactive protein |
CRS | Cytokine release syndrome |
Cy | Cyclophosphamide |
DOR | Duration of response |
EMA | European Medicines Agency |
FDA | Food and Drug Administration |
Flu | Fludarabine |
G-CSF | Granulocyte -colony stimulating factor |
GGT | Gamma-glutamyl transpeptidase |
GM-CSF | granulocyte-macrophage colony-stimulating factor |
HB | Hemoglobin |
HSCT | Hematopoietic stem cell transplantation |
HSCT | Hematopoietic stem cell transplantation |
HSCT | Hematopoietic stem cell transplantation |
ICANS | Immune effector cell associated neurotoxicity syndrome |
IFN-γ | Interferon-γ |
IL-10 | Interleukin-10 |
IL-6 | Interleukin-6 |
IQR | Interquartile |
MCP-1 | Monocyte chemoattractant protein 1 |
mCRS | Mild CRS |
MRD | Minimal residual disease |
NR | No remission |
NT-proBNP | N-terminal pro-brain natriuretic peptide |
ORR | Overall response rate |
OS | Overall survival |
PLT | Platelet |
PR | Partial remission |
PT | Prothrombin time |
r/r B-ALL | Relapsed or refractory B-cell acute lymphoblastic leukemia |
r/r DLBCL | Relapsed or refractory diffuse large B-cell lymphoma |
r/r MCL | Relapsed or refractory mantle-cell lymphoma |
scFv | Single chain variable fragment |
sCRS | Severe CRS |
SD | Standard deviation |
shRNA | Short hairpin RNA |
ssCAR-T-19 | IL-6 knocking down CD19 CAR-T |
TB | Total bilirubin |