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Transmission electron microscopic analysis of PK-8 spheres.
The surface of the cyst is formed by a single layer of PK-8 cells (A, arrowheads), and the adhesion between PK-8 cells in the spheres is weak (A, asterisks). PK-8 cells that had undergone degeneration (B, arrow) and necrosis (C, arrow). A large number of secretory granules were observed in PK-8 cells (D, arrows). Scale bar in A:10 μm, B, C, and D:2 μm.
