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. 2022 Aug 29;9:934270. doi: 10.3389/fmed.2022.934270

Table 3.

Relevant comparisons according to the pneumonia severity.

Characteristic Low risk PSI score High risk PSI score p-value
WBCs (×109/l), med, IQR 5.1 (3.9–7.5) 7.8 (5.8–13.8) 0.013
NETs (×109/l), med, IQR 3.85 (2.6–5.7) 5.9 (4.1–11.4) 0.016
LYMs (×109/l), med, IQR 0.8 (0.7–1.3) 0.8 (0.5–1.1) 0.306
PLTs (×109/l), med, IQR 167 (128–225) 190 (126–253) 0.534
D-dimer (mg/l), med, IQR 0.71 (0.56–1.72) 1.7 (0.58–4.1) 0.099
Ferritin (ug/l), med, IQR 417.5 (282–771) 893.5 (589.5–1,604.5) 0.008
IL-6 (ng/l), med, IQR 40.55 (14.6–91.1) 58.2 (38.4–130.0) 0.101
PCT (ng/ml), med, IQR 0.09 (0.06–0.25) 0.12 (0.09–0.22) 0.496
CRP (mg/l), med, IQR 56.15 (24.7–80.9) 79.4 (65.0–107.0) 0.038
C3 (g/l), mean ± SD 1.34 ± 0.29 1.17 ± 0.38 0.073
C4 (g/l), mean ± SD 0.27 ± 0.12 0.26 ± 0.11 0.774
IgG (g/l), mean ± SD 10.4 ± 3.1 9.6 ± 3.8 0.411
IgM (g/l), mean ± SD 1.2 ± 0.5 0.9 ± 0.5 0.031
IgA (g/l), mean ± SD 2.5 ± 1.0 2.6 ± 1.6 0.687
SII, med, IQR 651.1 (485.0–1,337.0) 1,626.7 (627–2,379.7) 0.024
NIH severity
Moderate 15 (57.7%) 4 (16.0%)
Severe/critical 11 (42.3%) 21 (84.0%) 0.002
Outcome
Recovery 24 (54.5%) 20 (45.5%)
Lethal outcome 2 (28.6%) 5 (71.4%) 0.248
ANA 7 (26.9%) 3 (12.0%) 0.291
ANCA 3 (13.6%) 2 (8.0%) 0.654
aCL IgG and/or IgM 3 (11.5%) 8 (32%) 0.076
aCL IgG 1 (3.8%) 7 (28.0%) 0.024
RF 2 (8.0%) 2 (8.3%) 1.0

WBCs, white blood cells; NETs, neutrophils; LYMs, lymphocytes; RBCs, red blood cells; Hgb, Hemoglobin; PLTs, platelets; PCT, procalcitonin; CRP, C-reactive protein.