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. 2022 Aug 29;12:887977. doi: 10.3389/fonc.2022.887977

Figure 1.

Figure 1

Schematic diagram of the experimental workflow employed in this study. (A) Collection of neoplastic tissues and peritumoral tissues from PTMC patients; (B) High-throughput sample including tissue grinding and lysis, and protein extraction and quantification; (C) Direct data-independent acquisition analysis of tissue proteomics and data processing; (D) Bioinformatics and statistical analyses; (E) Validation. PTMC, papillary thyroid microcarcinoma; LNM, lymph node metastasis.