Table 1.
Clinical and pathological characteristics of the subjects used for proteomics analysis.
| PTMC without LNM (n = 17) | PTMC with LNM (n = 16) | P-value | |
|---|---|---|---|
| Age at operation [y, ± S] | 40.59 ± 8.09 | 37.94 ± 7.56 | 0.339 |
| BMI [kg/m2, ± S] | 24.12 ± 3.01 | 23.50 ± 2.14 | 0.503 |
| Sex [n (%)] | 0.119 | ||
| Female | 12 (70.6) | 7 (43.8) | |
| Male | 5 (29.4) | 9 (56.2) | |
| Family history of thyroid disease [n (%)] | 0.758 | ||
| No | 12 (70.6) | 13 (81.3) | |
| Yes | 5 (29.4) | 3 (18.7) | |
| Tumor size [cm, ± S] | |||
| ≤ 0.5 | 8 (47.1) | 4 (25.0) | 0.188 |
| > 0.5 | 9 (52.9) | 12 (75.0) | |
| Clinical LNM [n (%)] | 0.227 | ||
| Absent | 17 (100.0) | 14 (87.5) | |
| Present | 0 (0.0) | 2 (12.5) | |
| Pathological subtype [n (%)] | 0.356 | ||
| Classic | 11 (64.7) | 13 (81.3) | |
| Follicular variant | 4 (23.5) | 1 (6.2) | |
| Classic and follicular variant | 2 (11.8) | 2 (12.5) | |
| Tumor location [n (%)] | 0.392 | ||
| Unifocal | 12 (70.6) | 9 (56.2) | |
| Multifocal | 5 (29.4) | 7 (43.8) | |
| Tumor calcification [n (%)] | 0.712 | ||
| Absent | 4 (23.5) | 2 (12.5) | |
| Present | 13 (76.5) | 14 (87.5) | |
| Microscopic capsular invasion [n (%)] | 0.226 | ||
| Absent | 5 (29.4) | 8 (50.0) | |
| Present | 12 (70.6) | 8 (50.0) | |
| Side of lobectomy [n (%)] | 0.881 | ||
| Unilateral | 7 (41.2) | 7 (43.8) | |
| Bilateral | 10 (58.8) | 9 (56.2) | |
| Hashimoto’s thyroiditis [n (%)] | 0.758 | ||
| Absent | 12 (70.6) | 13 (81.3) | |
| Present | 5 (29.4) | 3 (18.7) |
PTMC, papillary thyroid microcarcinoma; LNM, lymph node metastasis; BMI, body mass index. Data are presented as mean ± standard deviation, or n (%).