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. 2022 May 26;8(5):mgen000820. doi: 10.1099/mgen.0.000820

Table 4.

Functional enrichment analysis

Only significant data are reported in this table (those with a P value <0.05). All had P values of 0.00, corrected P values of 0.03 and an enrichment score of 3.49.

Clade

COGs function

Portion occurrence in group

Portion occurrence outside of group

Occurrence in group

Occurrence outside of group

Gene clusters IDs

Core in group

Core

C2

ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain

1

0.14

13

1

GC_00001559, GC_00002662

TRUE

FALSE

C2

Uncharacterized membrane protein YjiH, contains nucleoside recognition GATE domain

1

0

13

0

GC_00001582

TRUE

FALSE

C2

Predicted transposase YdaD

1

0

13

0

GC_00001531, GC_00001547

TRUE

FALSE

C2

DNA-binding transcriptional regulator, XRE-family HTH domain

1

0.14

13

1

GC_00001561, GC_00002218, GC_00002755

TRUE

FALSE

C2

Uncharacterized membrane protein YczE

1

0.14

13

1

GC_00001541

TRUE

FALSE

C2

Protein involved in initiation of plasmid replication

1

0.14

13

1

GC_00001513, GC_00001543, GC_00001550, GC_00001716, GC_00002180, GC_00002518, GC_00002635, GC_00002672

TRUE

FALSE

C2

Cys-tRNA(Pro) deacylase, prolyl-tRNA editing enzyme YbaK/EbsC

1

0

13

0

GC_00001567

TRUE

FALSE

C2

Phage-related protein, tail component

0.92

0.14

12

1

GC_00000083, GC_00001528, GC_00001843, GC_00002183, GC_00002230, GC_00002339

FALSE

FALSE

C2

Predicted epimerase YddE/YHI9, PhzF superfamily

1

0

13

0

GC_00001569

TRUE

FALSE

C2

Cell division protein DamX, binds to the septal ring, contains C-terminal SPOR domain

1

0

13

0

GC_00001573

TRUE

FALSE

C2

NADP-dependent 3-hydroxy acid dehydrogenase YdfG

1

0

13

0

GC_00001588

TRUE

FALSE

C2

DNA-binding transcriptional regulator, XRE family

1

0

13

0

GC_00001511

TRUE

FALSE

C2

Uncharacterized conserved protein, phosphatidylethanolamine-binding protein (PEBP) family

1

0

13

0

GC_00001584

TRUE

FALSE

C1

REP element-mobilizing transposase RayT

1

0

7

0

GC_00001768, GC_00002736

TRUE

FALSE

C1

ABC-type phosphate transport system, permease component

1

0

7

0

GC_00001724, GC_00001726

TRUE

FALSE

C1

Membrane-associated phospholipid phosphatase

1

0

7

0

GC_00001777

TRUE

FALSE

C1

Predicted pyrophosphatase or phosphodiesterase, AlkP superfamily

1

0

7

0

GC_00001732

TRUE

FALSE

C1

Secreted phosphatase, PhoX family

1

0

7

0

GC_00001783

TRUE

FALSE

C1

Predicted endonuclease, GIY-YIG superfamily

1

0

7

0

GC_00001627

TRUE

FALSE

C1

ABC-type spermidine/putrescine transport system, permease component II

1

0

7

0

GC_00001725

TRUE

FALSE

C1

Restriction endonuclease Mrr

1

0

7

0

GC_00001772

TRUE

FALSE

C1

ABC-type phosphate transport system, ATPase component

1

0

7

0

GC_00001727

TRUE

FALSE

C1

DNA modification methylase

1

0.08

7

1

GC_00001685

TRUE

FALSE

C1

Dienelactone hydrolase

1

0

7

0

GC_00001721

TRUE

FALSE

Colour highlights the genes present in all isolates in one clade but completely absent in the other clade. Two separate colours were used to differentiate those in clade one (red) and those in clade two.(blue).