TABLE 2.
Screening for Familial Hypercholesterolemia using centralized laboratory data.
| Author | Location and duration | Patients analyzed | LDLc cut-off point | DLCN | Genetic test (positives/solicited) |
|---|---|---|---|---|---|
| Scicali et al. (2018) | Catania (Italy) 48 months | 1,575 | >190 mg/dl& first degree child relatives with cLDL >160 mg/dl | Possibles + probables 56 | 26/56 (46%) |
| Gutierrez-Cortizo (2021) | Huelva (Spain) 36 months | 37,400 | >200 mg/dl | 654 possibles | 81/152 (53%) |
| 129 probables | |||||
| Sabatel Perez et al. (2021) | Toledo (Spain) 48 months | Unreported | >220 mg/dl | 285 possibles | 57/84 (68%) |
| 84 probables | |||||
| Arrobas-Velilla et al. (2021) (present study) | National (Spain) 24 months | 3,887,513 | >250 mg/dl | 262 possibles | 69/153 (45%) |
| 373 probables |
DLCN: ducth lipid clinic network score.