Table 2.
Comparison of different follow-up schedules including investigations and their intervals for patients with metastatic testicular germ cell tumour stratified by histologya
| Histology | STM/CTAP/CXR/CTC interval (mo) |
|||
|---|---|---|---|---|
| EAU/ESMO | NCCN | SWENOTECA | SAGTCCS | |
| Seminoma | ||||
| Year 1 | 3/6–12/6–12/6–12b | (3)/at 3 & 9 or 12/6/b | 6/6d/0/0 | 3/6/6/12b |
| Year 2 | 3/12/12/12b | (6)/12/6/b | 6/6d/0/0 | 3/12/12/12b |
| Year 3 | 6/12/12/0 | (6)/12/0/0 | 6/12d/0/0 | 6/12/12/12b |
| Year 4 | 6/0/0/0 | (6)/c/0/0 | 6/12d/0/0 | 6/0/0/0 |
| Year 5 | 6/12/12/12b | (6)/c/0/0 | 12/12d/0/0 | 6/12/12/12b |
| Year >5 | ||||
| Nonseminoma | ||||
| Year 1 | Same as for seminoma | 2/6/6/b | 2–3/6b/6/0 | 3/6/6/12b |
| Year 2 | 3/6–12/6/b | 3/6d/6/0 | 3/12/12/12b | |
| Year 3 | 6/12/(12)/b | 6/12d/12/0 | 6/12/12/12b | |
| Year 4 | 6/b/(12)/b | 6/12d/12/0 | 6/0/0/0 | |
| Year 5 | 6/b/0/0 (annual STM y5–y10) | 6/12d/12/0 | 6/12/12/12b | |
| Year >5 | ||||
STM = serum tumour markers; CTAP = abdominopelvic computed tomography; CXR = chest X-ray; CTC = chest CT; EAU = European Association of Urology; ESMO = European Society for Medical Oncology; NCCN = National Comprehensive Cancer Network; SWENOTECA = Swedish and Norwegian Testicular Cancer Group; SAGTCCS = Swiss Austrian German Testicular Cancer Cohort Study; y5 = year 5.
Optional investigations are in parentheses.
CTC in cases with pulmonary metastases at diagnosis (for NCCN: CTC instead of CXR in symptomatic patients or supradiaphragmatic disease at diagnosis).
As clinically indicated.
SWENOTECA explicitly recommends magnetic resonance imaging instead of CT.