FIGURE 6.

Docking analysis of the predicted binding of cinnamaldehyde analogs to FtsZ In silico docking studies were performed using OpenEye Scientific Software (McGann, 2012). Molecular binding of LXC 31 (6; gray) is shown above alongside co-crystallized FtsZ inhibitor PC190723 (green; PDB 3VOB) (Matsui et al., 2012). Binding poses for compounds 1 to 6 are shown in Supplementary Figure 4. In each case, the lowest energy pose of the lowest energy conformer is depicted.