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. 2022 Aug 29;12:974728. doi: 10.3389/fonc.2022.974728

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Copyright © 2022 Kusano, Katoh, Minohara, Fujii, Miyasaka, Takayama, Imura, Kusunoki, Miyakawa, Kamada, Serizawa, Takakusagi, Mizoguchi, Tsuchida and Yoshida

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Results of the clinical target volume (CTV) coverage (TC_CTV) and homogeneity index (HI) evaluation for the total dose. Figure panels (A, B) show the results of TC_CTV and HI, respectively. Figure panels (C, D) show the results of variations in TC_CTV (ΔTC_CTV) and HI (ΔHI) from the initial plan, respectively. These results were corrected for changes in factors other than gastrointestinal gas. For each replacement pattern, the median, first and third quartiles, maximum and minimum values, and outliers for (A) TC_CTV, (B) HI, (C) ΔTC_CTV, and (D) ΔHI are presented in a box-and-whisker plot. Statistical analyses were performed using the Friedman test. The symbol * indicate that there is a significant difference between them.