FIGURE 4.

Overview of detected potential biomarkers in asthma and MS. The model identified several proteins that have previously been identified in MS and asthma. The upper panel shows the potential biomarkers identified in MS and the lower panel shows the same in asthma. *mRNA expression, ¤ identified in mice. PBMCs, peripheral blood mononuclear cells. References stated in the figure ^aColamatteo A et al., J Immunol, 2019; ^bAchiron A et al., Ann N Y Acad Sci, 2007; ^cvan der Vuurst de Vries RM et al., JAMA Neurol, 2017; ^dWong YYM et al., Mult Scler, 2018; ^eMasuda H et al., J Neuroimmunol, 2017; ^fde JG-GJ et al., Immunobiology, 2018; ^gBomprezzi R et al., Hum Mol Genet, 2003; ^hWanke F et al., Cell Rep, 2017; ⁱAquino DA et al., J Neuropathol Exp Neurol, 1997; ^jBonetti B et al., Am J Pathol, 1999; ^kEnomoto Y et al., J Allergy Clin Immunol, 2009; ^lFerreira MA et al., Nat Genet. 2017; ^mPersson H et al., J Allergy Clin Immunol, 2015; ⁿMurray JT et al., Biochem J, 2004; ^oNestor CE et al., PLoS Genet, 2014; ^pPurwar R et al., PLoS One, 2011.