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. 2022 Aug 29;13:975560. doi: 10.3389/fendo.2022.975560

Table 3.

Complications and endocrine consequences of pituitary surgery Data are expressed as N (%).

All PatientsN = 63 Endoscopic Endonasal ApproachN=60 Microscopic Transcranial ApproachN=17
Surgical Complication
 Vascular injury
 Carotid artery injury
 Anterior choroidal artery injury
 Perforating artery
4 (6%)
0
0
4 (6%)
0 4 (24%)
0
0
4 (24%)
Hematoma
 Asymptomatic
 Symptomatic requiring surgery
6 (9%)
4 (6%)
2 (3%)
2 (4%)
1 (2%)
1 (2%)
4 (24%)
3 (18%)
1 (6%)
Visual deterioration
 Monocular
 Binocular
3 (5%) 0 3 (17%)
1 (6%)
2 (11%)
Motor deterioration
 Transient
 Persistent
5 (8%)
3 (5%)
2 (3%)
0 5 (29%)
3 (17%)
2 (12%)
Cognitive deterioration
 Transient
 Persistent
3 (5%)
1 (2%)
2 (3%)
0 3 (17%)
1 (6%)
2 (11%)
Cranial nerve palsy 3 (5%) 0 3 (18%)
Postoperative CSF leakage requiring plasty 4 (6%) 4 (7%) 0
Meningitis/Infection 3 (5%) 1 (2%) 2 (11%)
Epistaxis, rhinitis, sinusitis 1 (2%) 1 (2%) 0
Total complications
Severe complications*
13 (21%)
7 (11%)
6 (10%)
2 (3%)
7 (41%)
5 (29%)
Endocrine consequences of pituitary surgery
Anterior pituitary insufficiency
 One axis
 Two axes
 Panhypopituitarism
8 (13%)
6 (9%)
1 (2%)
1 (2%)
Diabetes insipidus
Transient
Persistent
15 (24%)
8 (13%)

Qualitative variables are expressed in absolute numbers (proportion).

*Severe complications included postoperative persistent neurological deficits (related to postoperative ischemia, traumatic surgical dissection or hematoma), hematomas requiring a second surgery, meningitis and surgical site infections.

In the bold values, the data are expressed in absolute numbers (N).