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. 2022 Aug 29;15:974007. doi: 10.3389/fnmol.2022.974007

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Copyright © 2022 Li, Liu, Chen, Dai, Zhao, Liu, Song, Xiong and Gao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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ST36 acupoints were sensitized in CFA model mice. (A) The mechanical pain threshold of the hind paw decreased in the CFA model. n = 20, ^****P < 0.0001, paired t-test. (B) The thermal pain threshold of the hind paw decreased in the CFA model. n = 20, ^****P < 0.0001, paired t-test. (C) The mechanical pain threshold of ST36 acupoints decreased in the CFA model. n = 6, ^***P = 0.0009, paired t-test. (D) The mechanical pain threshold of LST did not change significantly in the CFA model. n = 6, P = 0.7412, paired t-test. LST, the position 5 mm lateral side of the ST36.