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. 2022 Sep 12;12(40):25912–25922. doi: 10.1039/d2ra03656h

NO inhibitory activity of curcumin in microemulsion-based C. longa extracts (n = 9, mean ± SEM).

Microemulsion IC50 of Cur (nM) in the CL extract of HDESs-based MEs IC50 of HDESs-based MEs (%v/v)
HDES of octanoic acid:menthol (70:30, mass ratio)
ME-71 400 ± 90 0.0219 ± 0.0041
ME-72 270 ± 82 > 0.0371
ME-73 400 ± 67 > 0.0371
ME-74 300 ± 23 0.0277 ± 0.0051
HDES of octanoic acid:menthol (40:60, mass ratio)
ME-41 360 ± 32 0.0268 ± 0.0036
ME-42 230 ± 30 0.0222 ± 0.0023
ME-43 126 ± 1 0.0326 ± 0.0076
ME-44 216 ± 1 0.0260 ± 0.0031
HDES of octanoic acid:menthol (20:80, mass ratio)
ME-21 > 500 > 0.0371
ME-22 137 ± 1 0.0256 ± 0.0028
ME-23 75.2 ± 6.7 0.0136 ± 0.0023
ME-24 157 ± 4 0.00833 ± 0.00120
ME-25 220 ± 48 0.0288 ± 0.0055