Table 1. Partition Coefficients and Antiproliferative Activities of Test Compounds.

		IC50values (μM)
	logPo/wa	A2780 (ovary)	MDA-MB-231 (breast)	MRC-5 (normal lung)
G6AH1	1.07	5.2 ± 0.8	17 ± 2	26 ± 4
GA2AH1	0.85	5.3 ± 0.8	17 ± 3	33 ± 3
2DG6AH1	1.85	2.5 ± 0.6	22 ± 2	29 ± 4
AAH1	3.40	2.1 ± 0.2	12 ± 2	12 ± 2
DFO		3.5 ± 0.4	6.1 ± 0.4	9 ± 1

^aConsensus lipophilicity calculated by SwissADME.⁴⁰