FIGURE 1.

OPTN level decreased in degenerated NP tissue and increased in H₂O₂-teated rat NPCs. (A) different degrees of IVDD MRI images of patients. (B–C) Western blot and quantification of OPTN in human NP tissue. (D–G) Western blot and quantification of OPTN in rat NP tissues and H₂O₂-teated NPCs. Experiments involving human NP specimen were performed as means ± SD of 5 times in duplicates. Experiments involving rat NP specimen were performed as means ± SD of 3 times in duplicates. *p < 0.05, **p < 0.01, ***p < 0.001, ns p > 0.05.