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. 2022 Aug 29;13:941955. doi: 10.3389/fphar.2022.941955

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Copyright © 2022 Kweon, Kim, Oh, Oh, Kim, Mun, Bae and Park.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effect of ARP water extract on PSC activation and ECM production on the isolated PSCs. (A) PDGF-BB induced Acta-2, collagen I, and fibronectin one mRNA levels in isolated PSCs were assessed using RT-qPCR. (B) TGF-β induced Acta-2, collagen I, and fibronectin one mRNA levels in isolated PSCs were assessed using RT-qPCR. Data are represented as means ± SEM. Results are representative of three experiments. *p < 0.05 vs. distilled water alone; ^† p < 0.05 vs. PDGF-BB or TGF-β1.