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. 2022 Sep 12;21:37. doi: 10.1186/s12991-022-00415-0

Table 1.

Numbers (%) of drugs for mood stabilizers, antipsychotics, antidepressants and BZRAs divided by age and sex

Sex Age (years)
Males Females Significance  ≤ 39 40–64  ≥ 65 Significance
N = 1408 N = 1698 N = 676 N = 1899 N = 531
Mood stabilizers
 Lithium 718 (51.0%) 755 (44.5%)  < 0.001 287 (42.5%) 902 (47.5%) 284 (53.5%)  < 0.001
 Valproate 408 (29.0%) 474 (27.9%) 0.513 160 (23.7%) 575 (30.3%) 147 (27.7%) 0.004
 Lamotrigine 337 (23.9%) 397 (23.4%) 0.717 200 (29.6%) 465 (24.5%) 69 (13.0%)  < 0.001
 Carbamazepine 72 (5.1%) 77 (4.5%) 0.452 21 (3.1%) 103 (5.4%) 25 (4.7%) 0.053
Other medications
 Antipsychotics 777 (55.1%) 911 (53.6%) 0.393 387 (57.2%) 1075 (56.6%) 226 (42.5%)  < 0.001
 Antidepressants 566 (40.1%) 713 (41.9%) 0.312 271 (40.0%) 822 (43.2%) 186 (35.0%) 0.002
 BZRAs 969 (68.8%) 1236 (72.7%) 0.015 443 (65.5%) 1391 (73.2%) 371 (69.8%)  < 0.001

BZRAs, benzodiazepine receptor agonists