Table 2.
Pulmonary function test of patients at follow-up
| First follow-up (2 months) n = 377 |
Second follow-up (6 months) n = 312 |
Third follow-up (12 months) n = 284 |
p-value | |
|---|---|---|---|---|
| FVC, L | 3.50 (1.08) | 3.55 (1.02) | 3.66 (1.05) | < 0.001 |
| FVC, % pred | 98.99 (17.86) | 100.76 (16.49) | 104.16 (16.10) | < 0.001 |
| FVC < 80%, pred | 54 (14.32%) | 29 (9.29%) | 19 (6.69%) | < 0.001 |
| FEV1, L | 2.79 (0.86) | 2.81 (0.82) | 2.89 (0.84) | < 0.001 |
| FEV1, % pred | 98.58 (16.93) | 100.12 (16.07) | 103.53 (15.63) | < 0.001 |
| FEV1/FVC | 79.58 (6.87) | 79.03 (6.30) | 78.75 (5.92) | 0.004 |
| DLCO, % pred | 78.47 (19.14) | 81.61 (16.37) | 84.03 (16.37) | < 0.001 |
| DLCO < 80%, pred | 203 (53.80%) | 146 (46.79%) | 113 (39.78%) | < 0.001 |
| DLCO/VA, % pred | 92.55 (17.37) | 95.20 (17.25) | 95.66 (17.16) | 0.001 |
| DLCO/VA < 80%, pred | 83 (22.02%) | 57 (18.26%) | 48 (16.90%) | 0.02 |
| TLC, % pred | 95.61 (14.90) | 96.47 (14.33) | 96.88 (14.51) | 0.08 |
| RV, % pred | 96.90 (23.65) | 96.75 (23.18) | 95.02 (23.80) | 0.72 |
| 6MWT distance, m | 523.63 (94.30) | 520.57 (104.53) | 518.82 (101.66) | 0.004 |
| mMRCa | ||||
| 0–1 | 216 (78.54%) | 244 (88.72%) | 248 (90.18%) | < 0.001 |
| ≥ 2 | 59 (21.45%) | 31 (11.27%) | 27 (9.82%) | |
Data are n (%) or mean (SD)
FVC forced vital capacity, FEV1 forced expiratory volume in one second, DLCO diffusing capacity for carbon monoxide, VA alveolar volume, TLC total lung capacity, RV residual volume, 6MWT 6 min walk test (m), mMRC modified British Medical Research Council (dyspnea)
aDyspnea was registered on 275 patients