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. 2022 Sep 8;60(1):1690–1700. doi: 10.1080/13880209.2022.2112239

Figure 4.

Figure 4.

Kirenol could not reduce the blood glucose level of the diabetic mice, but it improved the renal damage of diabetic mice. (A) Blood glucose level of the mice. (B) Kidney/body weight ratios. (C) Renal pathological changes were analyzed by haematoxylin and eosin (H&E) staining and (D) periodic-acid Schiff (PAS) staining. Red arrow showed the mesangial expansion and the black arrows showed the focal interstitial inflammation. The content of serum creatinine (E) and urea nitrogen (F) was tested by using the commercially available kits. *p < 0.05 vs. control group, #p < 0.05 vs. DM group.