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. 2022 Sep 7;14(1):2120747. doi: 10.1080/19490976.2022.2120747

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© 2022 The Author(s). Published with license by Taylor & Francis Group, LLC.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — a) A representation of amoxicillin-loaded genipin-FCS/Hep NPs, the strategy and observations for H. pylori eradication using them, and the effects of amoxicillin solution alone and with/without amoxicillin-loaded genipin-FCS/Hep NPs in an H. pylori-induced gastric infection mouse model; b) Schematic illustration of SPIO/AMO@PAA/CHI nanoparticles in the gastric acid of gastric lumen; they adhere to and penetrate the mucus layer, become unstable, and release amoxicillin at the site of H. pylori infection. The distribution of the prepared FITC-SPIO/AMO@PAA/CHI in the mucin layer with/without exposure to a magnetic field for 5 and 10 min. c) Schematic illustration of the structure and bacterial biofilm eradication process of lipid polymer nanoparticles. (a) Reproduced with permission from ref,⁹⁶ © 2013, Elsevier Ltd. (b) Reproduced with permission from ref,⁹⁵ © 2020, American Chemical Society (c) Reproduced with permission from ref,⁹⁸ © 2019, Elsevier B.V.