Table 1.

The current regimens for H. pylori treatment.

Therapy	Components (usual Doses and Frequencies)	Days (n)	Reference
Clarithromycin triple therapy	Clarithromycin (500 mg bid)+amoxicillin (1 g bid) or metronidazole (500 mg bid)+PPI (standard dose bid)	14	47
Bismuth quadruple	Bismuth (300 mg qid)+metronidazole (500 mg tid or qid)+tetracycline (500 mg qid)+PPI (standard dose bid)	10 or 14	47
Levofloxacin triple	Levofloxacin (500 mg qd)+ amoxicillin (1 g bid)+ PPI (standard dose bid)	14	12
Levofloxacin quad	Levofloxacin (500 mg qd)+ PPI (standard dose bid)+ 2 antibiotics (multiple variations exist)	10 or 14	2
Concomitant therapy	Clarithromycin (500 mg bid)+ amoxicillin (1 g bid)+metronidazole or tinidazole (500 mg bid)+PPI (standard dose bid)	14	12
Sequential therapy	PPI (high-dose* qd) + amoxicillin (1 g bid); then PPI (standard dose bid)+ clarithromycin (500 mg bid)+nitroimidazole (500 mg bid)	5–7 then 5–7	12
Rifabutin triple	Rifabutin (150 or 300 mg qd), amoxicillin (1 g bid), PPI (standard dose bid)	10 or 14	47
High-dose dual	Amoxicillin (2 − 3 g daily in 3–4 split doses) PPI (high-dose* bid)	14	47
Vonoprazan dual therapy	Vonoprazan (20 mg bid)+amoxicillin (750 mg bid)	7	48
Vonoprazan triple therapy	Vonoprazan (20 mg bid) + amoxicillin (750 mg bid) + clarithromycin (200 mg bid)	7	48

*PPI standard dose is as follows: pantoprazole 40 mg, esomeprazole 20 mg, omeprazole 20 mg, lansoprazole 30 mg, rabeprazole 20 mg.dexlansoprazole 30 mg, “High-dose” implies double the standard dose; qd: once daily; bid: twice daily; tid: thirce daily; qid: four times daily