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Definition of primary efficacy end point. Freedom from transfusion represented an absence of any combination of RBC transfusions and/or platelet transfusions for at least 4 weeks. Transfusion of any type was not an inclusion criterion; however, freedom from transfusion was included in the end point because it is a clinical benefit. GVHD, graft versus host disease; LDH, lactate dehydrogenase; MAGIC, Mount Sinai Acute GVHD International Consortium; TMA, thrombotic microangiopathy.
