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. 2022 Sep 8;14:259–280. doi: 10.2147/BCTT.S380754

Table 1.

The Subtyping Schemes

Groups Name How is the Classification Made? Group Branches
Subtyping 1 Subtype Triple-Negative Triple-Negative
Not-Triple Negative
Subtyping 2 Original Subtype Triple-Negative
Luminal A
Luminal B
HER2-enriched
Subtyping 3 SubtypeHER2-enriched (received Herceptin) Triple-Negative
Luminal A
Luminal B
HER2-enriched (received Herceptin)
HER2-enriched (did not receive Herceptin)
Subtyping 4 Subtype HER2 positive-negative Triple-Negative
Luminal A
Luminal B HER2 positive
Luminal B HER2 negative
HER2-enriched (received Herceptin)
HER2-enriched (did not receive Herceptin)
Subtyping 5 Subtype received Herceptin Luminal B (received Herceptin)
Luminal B (did not receive Herceptin)
HER2-enriched (received Herceptin)
HER2-enriched (did not receive Herceptin)
HER2 negative