Figure 7.

QCT inhibited ferroptosis in PD mouse models by elevating Nrf2 expressions. (a) Representative immunoblots for the Nrf2 protein in SN of Ctrl, MPTP, and MPTP QCT groups. (b) Quantification of Nrf2 proteins in SN (n = 4). (c) Representative immunoblots for SLC7A11 and GPX4 proteins in SN of Ctrl, MPTP, and MPTP QCT groups. (d, e) Quantification of SLC7A11 and GPX4 proteins in SN (n = 4). (f, g) MDA, GSH, and SOD levels in SN tissues of Ctrl, MPTP, and MPTP QCT groups (n = 4). Data are presented as mean ± SEM. One-way ANOVA followed by Tukey's post hoc test. ^∗p < 0.05, ^∗∗p < 0.01, and ^∗∗∗p < 0.001; ns: no significant difference.