Table 2.
Data from 23 case reports of pregnant women with hyperemesis gravidarum (HG) treated with Mirtazapine. Maternal disease: two patients with type 1 diabetes and one patient with lyme disease. Obstetric pathology: gestational diabetes, preeclampsia, twinning, abnormal Doppler velocimetry, and multiple fetal malformations (trisomy 18). Neonatal complications: hyperexcitability and pulmonary hypertension.
| Variable | N | Yes | Total Percentage | Valid Percentage |
|---|---|---|---|---|
| Primiparous | 21 | 6 | 26.1% | 28.6% |
| Nulliparous | 21 | 9 | 39.1% | 42.8% |
| Previous HG | 19 | 7 | 36.8% | 30.4% |
| Previous interruption of pregnancy due to HG | 10 | 5 | 21.7% | 50% |
| Desire of interruption of current pregnancy | 11 | 7 | 30.4% | 63.3% |
| Depression | 14 | 13 | 56.5% | 92.8% |
| Anxiety | 11 | 10 | 43.5% | 90.1% |
| Weight loss | 11 | 11 | 47.8% | 100% |
| Laboratorial alteration | 3 | 3 | 13% | 100% |
| Dehydration | 3 | 3 | 13% | 100% |
| Parenteral nutrition | 12 | 7 | 30.4% | 58.3% |
| Use of intravenous mirtazapine | 21 | 5 | 21.7% | 23.8% |
| Clinical improvement with mirtazapine | 23 | 22 | 95.7% | 95.7% |
| Use of ondansetron | 16 | 9 | 39.1% | 56.3% |
| Maternal disease | 23 | 3 | 13% | 13% |
| Obstetric pathology | 23 | 5 | 21.7% | 21.7% |
| Cesarean delivery | 13 | 8 | 34.8% | 61.5% |
| Male newborn | 11 | 9 | 39.1% | 81.8% |
| Neonatal complication | 13 | 2 | 8.7% | 15.4% |