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. 2022 Sep 2;5:1422–1432. doi: 10.1016/j.crfs.2022.08.018

Fig. 2.

Fig. 2

Piperine improved fatty liver of high-fat diet-fed mice. (A) Liver sections was stained with HE. (B) Liver weight. (C) AST and (D) ALT in the serum. Hepatic mRNA levels of (E) SREBP-1c, (F) SREBP-2, (G) HMGCR, (H) CYP7A1, and (I) LDLR. Mean ± SD (n = 10). #p < 0.05, ##p < 0.01, ###p < 0.001, ####p < 0.0001 Model versus Normal; *p < 0.05, **p < 0.01, ***p < 0.001 versus Model; $ p < 0.05, PIP 40 (piperine at 40 mg/kg) versus PIP 20 (piperine at 20 mg/kg).