Table 2.
Frequency of Tau lesions in Mayo Clinic PSP brain bank
| Region/lesion N = 1565 |
Neurofibrillary tangles or pretangles | Coiled bodies | Tufted astrocytes | Threads | ||||
|---|---|---|---|---|---|---|---|---|
| Absent | Present | Absent | Present | Absent | Present | Absent | Present | |
| Peri-Rolandic cortices |
1% (20/1545) |
99% | 3.4% (53/1543) | 96% | 4% (56/1545) | 96% | 9% (137/1543) | 91% |
| Putamen |
0.1% (2/1560) |
99.9% | 2.2% (34/1562) | 98% | 1% (12/1562) | 99% | 9% (139/1561) | 91% |
| Globus pallidus |
0.4% (7/1555) |
99.6% | 5.4% (84/1554) | 95% |
42% (652/1554) |
58% | 4% (65/1554) | 96% |
| Subthalamic nucleus |
0.1% (2/1553) |
99.9% | 4.0% (62/1553) | 96% | 24% (374/1553) | 76% | 1% (8/1551) | 99% |
| Substantia nigra |
0.1% (1/1556) |
99.9% | 9.0% (140/1556) | 91% | 43% (663/1556) | 57% | 0.1% (2/1555) | 99.9% |
Absence versus presence of individual lesions in criteria specific regions. NA scores were excluded from calculations