Firing property of LEC fan cells is changed after CFA injection. A Representative traces showing the firing response of LEC fan cells to a 1-min rheobase stimulus. B, C Action potential (AP) numbers and mean interspike intervals (ISI) of LEC fan cells elicited by a 1-min rheobase stimulus. D CFA injection induces a marked leftward shift of the ISI cumulative distribution curve. E Representative traces showing the firing responses of LEC fan cells to a depolarizing current stimulus (+ 300 pA, 500 ms). F Fast afterhyperpolarization potential (fAHP, upper panel) and instantaneous frequency (Inst., lower panel) of AP firing in response to 100, 200, or 300 pA current injection. Data are from the first 6–9 spike intervals; #, number of spike intervals. fo, onset frequency; fss, steady-state frequency. *P < 0.05, **P < 0.01.