Fig. 4.
Effects of dopamine D1 and D2 receptor agonists on Ih and onset frequency of LEC fan cells in the CFA group. A, E Changes in Ih of LEC fan cells during bath application of 30 µmol/L SKF38393 or 10 µmol/L quinpirole. Right panel, amplified current amplitude at − 120 mV. C, G Changes in the firing of LEC fan cells during bath application of 30 µmol/L SKF38393 or 10 µmol/L quinpirole. Right panel, amplified onset frequency. Spikes are elicited by a 200-pA depolarizing stimulus (500 ms in duration). B Ih amplitude in pre-drug, SKF38393, and washout in fan cells at − 120 mV. ** vs pre. For this and the following figures in this format, the grey circles represent data from individual cells. D Onset frequency in pre-drug, SKF38393, and washout in fan cells. ** vs pre. F Ih amplitude in pre-drug, quinpirole, and washout in fan cells at − 120 mV. ** vs pre. H Onset frequency in pre-drug, quinpirole, and washout in fan cells. ** vs pre. **P < 0.01.