TABLE 1.
Clinicopathological characteristics of patients with HCC (n = 149).
| Clinicopathological characteristics | Case no. (%) |
|---|---|
| Age, median (range, years) | 55 (28–87) |
| Sex | |
| Male | 112 (75.2%) |
| Female | 37 (24.8%) |
| Etiological factors | |
| HBV | 123 (82.6%) |
| HCV | 7 (4.7%) |
| Alcohol intake | 10 (6.7%) |
| None | 9 (6.0%) |
| Underlying diseases | |
| Cirrhosis | 131 (87.9%) |
| Hepatitis | 15 (10.1%) |
| None | 3 (2.0%) |
| AFP level | |
| <400 | 97 (65.1%) |
| ≥400 | 34 (22.8%) |
| Not reported | 18 (12.1%) |
| Child-Pugh class | |
| A | 138 (92.6%) |
| B | 11 (7.4%) |
| BLCL stage | |
| A | 85 (57.0%) |
| B | 5 (3.4%) |
| C | 59 (39.6%) |
| Tumor size, mean (range, cm) | 4.5 (0.7–22.0) |
| Histological grade (Edmondson and Steiner grading system) | |
| Grade 1 | 12 (8.1%) |
| Grade 2 | 54 (36.2%) |
| Grade 3 | 70 (47.0%) |
| Grade 4 | 13 (8.7%) |
| Vessel invasion | |
| Present | 59 (39.6%) |
| Not identified | 90 (60.4%) |
| Perineural invasion | |
| Present | 4 (2.7%) |
| Not identified | 145 (97.3%) |
| Tumor focality | |
| Single | 125 (83.9%) |
| Multiple | 24 (16.1%) |
| Proliferation index (Ki-67 index) | |
| <1% | 114 (76.5%) |
| ≥1% | 35 (23.5%) |
| Stage (AJCC 8th edition) | |
| IA | 22 (14.8%) |
| IB | 59 (39.6%) |
| II | 45 (30.2%) |
| IIIA | 6 (4.0%) |
| IIIB | 17 (11.4%) |
| Additional treatments | |
| None | 65 (43.6%) |
| Radiofrequency ablation | 5 (3.4%) |
| Chemoembolization | 68 (45.6%) |
| Systemic chemotherapy | 6 (4.0%) |
| Combined | 5 (3.4%) |
HCC, hepatocellular carcinoma; HBV, hepatitis B virus; HCV, hepatitis C virus; AFP, alpha-fetoprotein; BLCL, Barcelona Clinic Liver Cancer; AJCC, American Joint Committee on Cancer.