Table 1.
Modified aGVHD Glucksberg grading scale.
| Grade | Cumulative organ | ||
|---|---|---|---|
| Skin | Liver–bilirubin μmol/L (mg/dl) | Gastrointestinal—amount of diarrhea | |
| 1 | Rash area < 25% | 34–50 (2–2.9) | 500–1000 ml/d or pathologically confirmed upper gastrointestinal GVHD |
| 2 | Rash area 25–50% | 51–102 (3–6) | 1000–1500 ml/d |
| 3 | Rash area > 50%, body erythema | 103–255 (6.1–15) | 1500–2000 ml/d |
| 4 | Generalized erythema with blister formation or exfoliation | > 255 (> 15) | > 2000 ml/d or severe abdominal pain with + intestinal obstruction |
| Degree | |||
| 0 (no) | 0 | 0 | 0 |
| I (light) | 1–2 | 0 | 0 |
| II (medium) | 1–3 | or 1 | or 1 |
| III (serious) | 2–3 | 2–3 | or 2–4 |
| IV (fatal) | 4 | or 4 | – |