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. 2022 Sep 12;12:15316. doi: 10.1038/s41598-022-19059-x

Table 2.

Comparison of clinical data between AKI group and non-AKI group.

Non-AKI group (N = 102) AKI group (N = 42) P-value
Gender
Female 52 (51%) 17 (40%) 0.335
Male 50 (49%) 25 (60%)
Age
 < 20y 14 (14%) 7 (17%) 0.747
20–50y 77 (75%) 32 (76%)
 > 50y 11 (11%) 3 (7%)
Weight
 ≤ 50 kg 69 (68%) 29 (69%) 1
 > 50 kg 33 (32%) 13 (31%)
FK506
No 85 (83%) 23 (55%)  < 0.001**
Yes 17 (17%) 19 (45%)
Donor source
Auto 21 (21%) 0 (0%) 0.003*
Allo 81 (79%) 42 (100%)
Stem cell source
PB 26 (25%) 13 (31%) 0.643
PB + BM 76 (75%) 29 (69%)
HLA
Mismatch 9 (9%) 14 (33%)  < 0.001**
Match 93 (91%) 28 (67%)
Blood type matching
No 28 (27%) 25 (60%)  < 0.001**
Yes 74 (73%) 17 (40%)
aGVHD
No 83 (81%) 21 (50%)  < 0.001**
Yes 19 (19%) 21 (50%)
HC
No 90 (88%) 35 (83%) 0.604
Yes 12 (12%) 7 (17%)
Vancomycin
No 46 (45%) 17 (40%) 0.746
Yes 56 (55%) 25 (60%)
Sepsis
No 94 (92%) 37 (88%) 0.65
Yes 8 (8%) 5 (12%)
Infection
No 33 (32%) 2 (5%)  < 0.001**
Yes 69 (68%) 40 (95%)
Ganciclovir
No 29 (28%) 9 (21%) 0.51
Yes 73 (72%) 33 (79%)
TBI
No 77 (75%) 28 (67%) 0.381
Yes 25 (25%) 14 (33%)
CSA
No 44 (43%) 21 (50%) 0.57
Yes 58 (57%) 21 (50%)
Triazole antifungals
No 24 (24%) 5 (12%) 0.176
Yes 78 (76%) 37 (88%)
Amphotericin B
No 100 (98%) 40 (95%) 0.71
Yes 2 (2%) 2 (5%)
Implantation syndrome
No 99 (97%) 41 (98%) 1
Yes 3 (3%) 1 (2%)
Secondary diabetes
No 100 (98%) 39 (93%) 0.297
Yes 2 (2%) 3 (7%)
Secondary hypertension
No 89 (87%) 38 (90%) 0.795
Yes 13 (13%) 4 (10%)
Cytomegaloviremia
No 78 (76%) 24 (57%) 0.034*
Yes 24 (24%) 18 (43%)
Basal creatinine
44–106 μmol/L 87 (85%) 33 (79%) 0.461
 < 44 μmol/L 15 (15%) 9 (21%)

Tacrolimus (FK506), acute graft versus host disease (aGVHD), hemorrhagic cystitis (HC), total body irradiation (TBI), cyclosporin A(CSA).

*P < 0.05, **P < 0.01.