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. 2022 Aug 30;13:998236. doi: 10.3389/fimmu.2022.998236

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Copyright © 2022 Wang, Lu, Wang, Liu, Wu, Yang, Huan and Gong

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Characteristics of CuproptosisCluster in TCGA-glioma cohort. (A) The correlations among the ten cuproptosis-related genes (CRGs). The color represents the correlation coefficient. (B) Cluster diagram for subtype analysis of glioma samples. The intragroup correlations were the highest and the inter-group correlations were low when k=2. (C) PCA analysis for the two subclusters. (D) Kaplan-Meier survival curve showing survival probability of cluster1 and cluster2. (E) Heatmap showing the expression levels of the ten cuproptosis-related genes (CRGs) in different clinical features and clusters. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001.