TABLE 2.
Logistic regressions for the effects of baseline lipid parameters and new-onset carotid plaque.
| Lipid parameters | N (%) | OR (95% CI) P-value |
||
| Crude | Adjusted model 1 | Adjusted model 2 | ||
| RC, per 1 mmol/L increase | 188 (21.56%) | 1.65 (1.10–2.48) 0.016 | 1.52 (1.02–2.28) 0.042 | 1.57 (1.03–2.41) 0.038 |
| Tertiles of RC | ||||
| T1 (< 0.42) | 46 (15.86%) | Ref. | Ref. | Ref. |
| T2 (0.42–< 0.64) | 50 (17.24%) | 1.11 (0.71–1.71) 0.655 | 1.07 (0.69–1.67) 0.764 | 1.23 (0.78–1.95) 0.376 |
| T3 (≥ 0.64) | 92 (31.51%) | 2.44 (1.64–3.64) < 0.001 | 2.18 (1.45–3.28) < 0.001 | 2.53 (1.63–3.95) < 0.001 |
| p for trend | < 0.001 | < 0.001 | < 0.001 | |
| TC, per 1 mmol/L increase | 188 (21.56%) | 1.28 (1.08–1.54) 0.006 | 1.30 (1.08–1.56) 0.006 | 1.28 (1.06–1.55) 0.011 |
| Tertiles of TC | ||||
| T1 (< 4.87) | 50 (17.30%) | Ref. | Ref. | Ref. |
| T2 (4.87–< 5.60) | 59 (20.21%) | 1.21 (0.80–1.84) 0.370 | 1.25 (0.81–1.91) 0.313 | 1.23 (0.79–1.90) 0.355 |
| T3 (≥ 5.60) | 79 (27.15%) | 1.78 (1.19–2.66) 0.005 | 1.81 (1.19–2.76) 0.005 | 1.81 (1.18–2.78) 0.007 |
| p for trend | 0.004 | 0.005 | 0.006 | |
| TG, per 1 mmol/L increase | 188 (21.56%) | 1.15 (1.01–1.31) 0.040 | 1.12 (0.97–1.28) 0.115 | 1.12 (0.97–1.30) 0.128 |
| Tertiles of TG | ||||
| T1 (< 0.99) | 45 (15.68%) | Ref. | Ref. | Ref. |
| T2 (0.99–< 1.55) | 64 (21.92%) | 1.51 (0.99–2.30) 0.056 | 1.49 (0.97–2.29) 0.070 | 1.55 (0.99–2.41) 0.053 |
| T3 (≥ 1.55) | 79 (26.96%) | 1.99 (1.32–2.99) 0.001 | 1.79 (1.18–2.72) 0.006 | 1.92 (1.22–3.00) 0.004 |
| p for trend | 0.001 | 0.007 | 0.005 | |
| HDL-C, per 1 mmol/L increase | 188 (21.56%) | 0.63 (0.41–0.96) 0.032 | 0.73 (0.46–1.15) 0.175 | 0.64 (0.39–1.05) 0.079 |
| Tertiles of HDL-C | ||||
| T1 (< 1.28) | 69 (23.88%) | Ref. | Ref. | Ref. |
| T2 (1.28–< 1.60) | 69 (23.79%) | 1.00 (0.68–1.46) 0.982 | 1.03 (0.69–1.55) 0.867 | 0.96 (0.64–1.46) 0.863 |
| T3 (≥ 1.60) | 50 (17.06%) | 0.66 (0.44–0.99) 0.042 | 0.74 (0.48–1.15) 0.183 | 0.65 (0.41–1.05) 0.077 |
| p for trend | 0.046 | 0.188 | 0.0780 | |
| LDL-C, per 1 mmol/L increase | 188 (21.56%) | 1.43 (1.15–1.78) 0.001 | 1.40 (1.12–1.76) 0.003 | 1.40 (1.11–1.77) 0.004 |
| Tertiles of LDL-C | ||||
| T1 (< 2.85) | 50 (17.42%) | Ref. | Ref. | Ref. |
| T2 (2.85–< 3.46) | 58 (19.80%) | 1.17 (0.77–1.78) 0.463 | 1.10 (0.72–1.69) 0.666 | 1.14 (0.73–1.76) 0.567 |
| T3 (≥ 3.46) | 80 (27.40%) | 1.79 (1.20–2.67) 0.004 | 1.70 (1.13–2.57) 0.012 | 1.75 (1.14–2.67) 0.010 |
| p for trend | 0.004 | 0.010 | 0.009 | |
| Non-HDL-C, per 1 mmol/L increase | 188 (21.56%) | 1.39 (1.16–1.65) < 0.001 | 1.35 (1.12–1.61) 0.001 | 1.36 (1.13–1.65) 0.001 |
| Tertiles of Non-HDL-C | ||||
| T1 (< 3.37) | 49 (16.96%) | Ref. | Ref. | Ref. |
| T2 (3.37–< 4.10) | 57 (19.52%) | 1.19 (0.78–1.81) 0.424 | 1.09 (0.71–1.68) 0.696 | 1.14 (0.73–1.77) 0.571 |
| T3 (≥ 4.10) | 82 (28.18%) | 1.92 (1.29–2.87) 0.001 | 1.81 (1.20–2.73) 0.005 | 1.89 (1.23–2.89) 0.004 |
| p for trend | 0.001 | 0.003 | 0.003 | |
Model 1: adjusted for age and sex. Model 2: adjusted for age, sex, body mass index, current drinking, current smoking, estimated glomerular filtration rate, diabetes mellitus, hypertension, antihypertensive, and hypoglycemic drugs.
OR, odds ratio; CI, confidence interval; Ref., reference value; RC, remnant cholesterol; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Non-HDL-C, non-high-density lipoprotein cholesterol.