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. 2022 Aug 30;9:903390. doi: 10.3389/fcvm.2022.903390

TABLE 3.

Comparisons of remnant lipoprotein cholesterol (RC) and another lipid parameter in relation to new-onset carotid plaque.

Comparisons OR (95% CI) P-value OR (95% CI) P-value
Comparison I† (when considered RC and TC simultaneously)
RC, mmol/L TC, mmol/L
T1 (< 0.42) Ref. T1 (< 4.87) Ref.
T2 (0.42–< 0.64) 1.16 (0.73–1.86) 0.525 T2 (4.87–< 5.60) 1.12 (0.72–1.75) 0.611
T3 (≥ 0.64) 2.26 (1.40–3.65) < 0.001 T3 (≥ 5.60) 1.33 (0.83–2.12) 0.230
Comparison II† (when considered RC and TG simultaneously)
RC, mmol/L TG, mmol/L
T1 (< 0.42) Ref. T1 (< 0.99) Ref.
T2 (0.42–< 0.64) 1.16 (0.70–1.94) 0.564 T2 (0.99–< 1.55) 1.26 (0.77–2.07) 0.363
T3 (≥ 0.64) 2.55 (1.41–4.61) 0.002 T3 (≥ 1.55) 1.01 (0.55–1.85) 0.963
Comparison III† (when considered RC and HDL-C simultaneously)
RC, mmol/L HDL-C, mmol/L
T1 (< 0.42) Ref. T1 (< 1.28) Ref.
T2 (0.42–< 0.64) 1.21 (0.75–1.94) 0.428 T2 (1.28–< 1.60) 1.22 (0.79–1.88) 0.377
T3 (≥ 0.64) 2.54 (1.55–4.15) < 0.001 T3 (≥ 1.60) 1.02 (0.60–1.74) 0.929
Comparison IV† (when considered RC and LDL-C simultaneously)
RC-mmol/L LDL-C, mmol/L
T1 (< 0.42) Ref. T1 (< 2.85) Ref.
T2 (0.42–< 0.64) 1.14 (0.71–1.84) 0.578 T2 (2.85–< 3.46) 1.07 (0.68–1.67) 0.772
T3 (≥ 0.64) 2.25 (1.39–3.63) < 0.001 T3 (≥ 3.46) 1.33 (0.84–2.11) 0.230
Comparison V† (when considered RC and Non-HDL-C simultaneously)
RC, mmol/L Non-HDL-C, mmol/L
T1 (< 0.42) Ref. T1 (< 3.37) Ref.
T2 (0.42–< 0.64) 1.19 (0.72–1.96) 0.494 T2 (3.37–< 4.10) 0.94 (0.59–1.52) 0.811
T3 (≥ 0.64) 2.28 (1.31–3.97) 0.004 T3 (≥ 4.10) 1.17 (0.68–2.00) 0.569

†RC and other lipid parameters were simultaneously added into the multivariable regression model. The model was adjusted for age, sex, body mass index, current drinking, current smoking, estimated glomerular filtration rate, diabetes mellitus, hypertension, antihypertensive, and hypoglycemic drugs.

OR, odds ratio; CI, confidence interval; Ref., reference value; RC, remnant cholesterol; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Non-HDL-C, non-high-density lipoprotein cholesterol.