TABLE 3.
Associations between molecular and clinical characteristics
| Clinical parameters | Mutational status | p value | ||||
|---|---|---|---|---|---|---|
| EGFR mutation (n = 140) | ALK translocation (n = 107) | ROS1 translocation (n = 44) | MET ex14Δ (n = 31) | No mutations (n = 1827) | ||
| Age, median (range) | 65 (29–88) | 58 (26–80) | 59 (30–78) | 71 (56–84) | 63 (16–85) | 1.2·10−14 (Kruskal–Wallis rank sum test) |
| Gender | ||||||
| Men | 31 (22.1%) | 39 (36.4%) | 11 (25%) | 11 (35.5%) | 1319 (72.2%) | <2.2·10−16 (χ2 test) |
| Women | 109 (77.9%) | 68 (63.6%) | 33 (75%) | 20 (64.5%) | 508 (27.8%) | |
| Smoking status | ||||||
| Ever | 9 (42.9%) | 10 (24.4%) | 2 (20%) | 3 (37.5%) | 392 (54.7%) | 0.00025 (Fisher's Exact Test) |
| Never | 12 (57.1%) | 31 (75.6%) | 8 (80%) | 5 (62.5%) | 324 (45.3%) | |