Table 1.
Patient number | Age/sex | Time after COVID-19 vaccination | Type of vaccination | Clinical features | Immunological features | EULAR/ACR SLE classification criteria | Treatment | SLEDAI 2K (first visit) | SLEDAI 2K (last visit) |
---|---|---|---|---|---|---|---|---|---|
1 | 24/m | Seven days after the first dose | Pfizer BNT162b2 mRNA | Psoriasiform papulosquamous rash, a non-scarring alopecia, arthritis | Positive ANA 1/160, Ribosomal P, chromatin, and low C3 | 13 | HCQ 200 mg BID, topical steroids, and etoricoxib | 10 | 4 |
2 | 23/m | One month after the second dose | Pfizer BNT162b2 mRNA | Pancytopenia, fever, malar rash, oral ulcers, non-resolving headache, lymphadenopathy | Positive ANA 1/160, Ro/SSA, beta 2 glycoprotein IgG, direct Coombs | 14 | HCQ 200 mg BID, Prednisone 1 mg/kg, azathioprine 2 mg/kg, Granulocyte colony-stimulating factor and revolade | 15 | 1 |
3 | 56/m | One month after second dose | Pfizer BNT162b2 mRNA | Arthritis, lymphadenopathy | Positive ANA 1/160, double-stranded DNA, smith, low c3 | 15 | HCQ 200 mg BID and etoricoxib | 8 | 4 |
COVID-19 coronavirus 19, ANA antinuclear antibodies, EULAR/ACR European League Against Rheumatism and the American College of Rheumatology, BID twice daily, DNA deoxyribonucleic acid, mRNA messenger ribonucleic acid, SLEDA 2K systemic lupus erythematosus disease activity index 2000, HCQ hydroxychloroquine