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. 2022 Aug 30;12:953962. doi: 10.3389/fcimb.2022.953962

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Copyright © 2022 Zhu, Han, Liu, Fan, Shi and Li

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Alpha and beta diversity analysis of the intestinal flora in stool samples from ulcerative colitis patients. (A–D). Results of alpha diversity analysis of intestinal flora as evaluated by Chao 1, observed species, PD Whole Tree, and the Shannon Diversity Index. The diversity of intestinal flora in UC patients in remission was found to be significantly reduced. (E, F). Results of beta diversity analysis. PCA based on OTU leve, and PCoA based on Bray–Curtis distance. Points of different colors or shapes represent different sample groupings, and the scales of the horizontal and vertical axes are relative distances. AUC, UC patients with active disease; RUC, UC patients in remission; and HC, healthy control subjects.