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. 2022 Jul 25;15(9):2075–2095. doi: 10.1111/cts.13357

FIGURE 5.

FIGURE 5

Proposed design for clinical DDI studies with alternative CYP3A inducers (a) carbamazepine; (b) phenytoin and lumacaftor with CYP3A substrates. PK, pharmacokinetic.