TABLE 3.

List of genes and mutant phenotypes related to fetal nuchal edema with anemia or blood vascular endothelial barrier anomalies in mice (loss-of-function mutations if not stated).

Gene	Mutant phenotype	References
Stk40	Anemia; small liver with increased cell apoptosis	Wang et al., 2017
Flt1	Enhanced vascular permeability	Otowa et al., 2016
Myc	(Gain-of-function) Disruption of BEC junctions	Kokai et al., 2009
Enah; Evl; Vasp	Disruption of BEC junctions	Furman et al., 2007

BEC, blood vascular endothelial cell.