FIGURE 2.

The expression levels of each member of the CMTM family at the mRNA and protein levels in ovarian cancer tissue and normal ovarian tissue. (A) Box plot of mRNA expression of different CMTM family members in OV tissue (n = 426) and normal ovarian tissue (n = 88) based on the GEPIA database. Compared with normal samples, the mRNA expression of CMTM6/7/8 was found to be relatively high in OV tissue at the mRNA level (*p < 0.05). (B) Immunohistochemical stained sections of CMTM1/3/4/6 in OV tissue and normal ovarian tissue based on HPA database. It can be seen that the higher staining intensity in OV tissue means that CMTM1/3/4/6 was relatively highly expressed at the protein level in ovarian cancer. The ID of the sample and the antibody used were recorded. CMTM1 (ID: 2713; ID: 1310; Antibody: HPA13801), CMTM3 (ID: 2004; ID: 3116; Antibody: HPA072695), CMTM4 (ID: 2159; ID: 1844; Antibody: HPA023890, HPA014704), CMTM6 (ID: 2713; ID: 2347; Antibody: HPA026980).