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. 2022 Aug 30;13:918319. doi: 10.3389/fgene.2022.918319

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Copyright © 2022 Zhang, Wang, Yue and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The correlation between the expression level of each member of the CMTM family and the degree of immune infiltration of multiple immune cells or the expression of immune checkpoint genes in ovarian cancer tissues. (A) The correlation between the expression level of each member of the CMTM family in ovarian cancer tissues and the degree of immune infiltration of a variety of immune cells, including B cells, CD8+T cells, CD4+T cells, macrophages, neutrophils, and dendritic cells. (B) The correlation between the expression level of CMTM and the genes PDCD1, CD274, and PDCD1LG2 that encode the immune checkpoints of PD1, PDL1, and PDL2. Spearman’s method was used for correlation analysis. Partial. cor >0 was considered a positive correlation. Partial. cor <0 was considered a negative correlation. p < 0.05 was considered statistically significant.