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. 2022 Aug 30;13:933998. doi: 10.3389/fphar.2022.933998

TABLE 2.

Values of the patients’ laboratory parameters and vitals at baseline and at the end of the study.

Baseline After 5–7 days of treatment At discharge
Control Vitamin A Zinc p value Control Vitamin A Zinc p value Control Vitamin A Zinc p value
ALT (U/L) 36.2 (6.52) 35.7 (5.99) 37.1 (7.85) 0.76 35.7 (6.68) 35.0 (6.69) 35 (7.12) 0.93 34.4 (4.96) 33.7 (5.22) 33.8 (6.16) 0.88
AST (U/L) 38.6 (4.86) 38.4 (6.27) 39.4 (8.35) 0.85 37.4 (6.05) 37.2 (5.62) 36.2 (5.66) 0.74 34.2 (5.70) 35.2 (3.81) 35.2 (4.78) 0.71
BUN (mg/dl) 9.68 (1.55) 9.60 (1.08) 9.56 (1.42) 0.95 9.56 (1.04) 9.52 (0.82) 9.04 (0.98) 0.11 9.44 (0.82) 9.2 (1.00) 9.24 (0.88) 0.61
CRP (mg/L) 64.4 (59.9) 61.7 (42.9) 71.5 (54.0) 0.79 36.8 (37.4) 33.5 (33.2) 23.4 (20.9) 0.29 7.83 (2.34) 7.21 (2.64) 8.9 (4.41) 0.19
Hb (g/dl) 11.9 (1.35) 11.6 (1.34) 11.5 (1.73) 0.48 11.1 (1.14) 11.0 (1.45) 11.2 (1.5) 0.96 11.6 (0.92) 11.3 (1.1) 10.9 (2.44) 0.35
PCO2 (mmHg) 50.0 (17.3) 52.4 (16.0) 50.2 (17.9) 0.86 46.6 (8.75) 43.9 (8.05) 41.9 (6.49) 0.11 39.0 (1.9) 38.5 (2.47) 39.3 (3.95) 0.61
PH 7.27 (0.18) 7.18 (0.19) 7.23 (0.18) 0.22 7.35 (0.07) 7.35 (0.06) 7.37 (0.07) 0.40 7.40 (0.01) 8.61 (6.00) 7.40 (0.01) 0.37
Plt (×106/L) 289 (68.4) 310 (73.7) 265 (98.4) 0.16 269 (76.2) 284 (71.6) 249 (97.7) 0.33 285 (85.1) 256 (76.4) 251 (111) 0.36
PO2 (mmHg) 59.5 (44.0) 45.2 (12.3) 55.8 (35.6) 0.30 75.1 (13.7) 78.2 (16.9) 85.6 (15.7) 0.05 96.0 (4.33) 95.1 (7.54) 95.7 (3.82) 0.86
RR (BPM) 47.7 (9.62) 47.2 (10.4) 48.8 (7.23) 0.82 37.6 (8.94) 36.8 (9.13) 34.5 (6.37) 0.40 34.4 (8.28) 32.7 (6.99) 32.4 (5.69) 0.55
SO2 (%) 80.5 (8.81) 79.3 (8.62) 80.8 (9.39) 0.82 94.4 (4.96) 93.4 (7.37) 97.1 (2.60) 0.32 98.4 (1.12) 94.8 (17.5) 98.5 (1.48) 0.34
SCr (mg/dl) 0.46 (0.11) 0.46 (0.10) 0.46 (0.10) 0.95 0.44 (0.06) 0.46 (0.08) 0.428 (0.08) 0.32 0.43 (0.05) 0.428 (0.05) 0.42 (0.08) 0.87
T (°C) 38.4 (0.88) 37.9 (0.95) 37.9 (0.78) 0.08 37.1 (0.15) 35.9 (6.00) 37.1 (0.16) 0.36 37.0 (0.10) 35.8 (6.02) 35.5 (5.88) 0.50
TLC (×106/L) 22.4 (7.24) 22.5 (8.02) 40.2 (93.1) 0.41 15.7 (7.06) 14.0 (7.53) 27.5 (72.7) 0.47 8.44 (1.63) 7.52 (1.68) 18.9 (54.6) 0.37

*Statistical test used was one-way analysis of variance (ANOVA).