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. 2022 Aug 26;24(4):639. doi: 10.3892/etm.2022.11576

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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PGG improves renal function in diabetic rats. (A) The body weight of DN rats with or without PGG treatment. (B) The blood glucose in DN rats with or without PGG treatment was detected by a blood glucose meter. The (C) ACR and levels of (D) BUN and Scr in DN rats with or without PGG treatment was measured by an automatic biochemical analyzer. (E) The expression of nephrin in DN rats with or without PGG treatment was analyzed by western blotting. ^*P<0.05, ^**P<0.01 and ^***P<0.001. PGG, 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose; DN, diabetic nephropathy ACR, albumin/creatinine ratio; BUN, blood urea nitrogen; Scr, serum creatinine; GRE, Galla rhois extract; -L, low; 5 mg/kg; -H, high; 20 mg/kg.