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. 2022 Aug 26;24(4):639. doi: 10.3892/etm.2022.11576

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Copyright: © Wang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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PGG improves renal pathological changes in diabetic rats. The pathological changes, fibrosis and collagen deposition in renal tissues were in turn detected by (A) hematoxylin and eosin, (B) periodic acid-Schiff and (C) Masson staining. Magnification, x400. (D) The expression of fibrosis related proteins in DN rats with or without PGG treatment was detected by western blotting. ^**P<0.01 and ^***P<0.001. PGG, 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose; DN, diabetic nephropathy; GRE, Galla rhois extract; -L, low; 5 mg/kg; -H, high; 20 mg/kg.