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PGG regulates the MAPK/NF-κB and ERK/Nrf2/HO-1 signaling pathways. The expression of related proteins in MAPK/NF-κB and ERK/Nrf2/HO-1 signaling pathways in DN rats with or without PGG treatment was detected by western blotting. **P<0.01 and ***P<0.001. PGG, 1, 2, 3, 4, 6-penta-O-galloyl-β-D-glucose; Nrf2, nuclear factor erythroid-derived 2-related factor 2; HO-1, hemeoxygenase-1; DN, diabetic nephropathy; p-, phosphorylated; t-, total.
